Randomized controlled trial: Flexible sigmoidoscopy as an adjunct to faecal occult blood testing in population screening

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منابع مشابه

Sigmoidoscopy and faecal occult blood test - a comparative screening trial.

Geir Hoff Telemark Hospital Trust and Cancer Registry of Norway and University of Oslo Colorectal cancer is a major health issue, both globally and in Norway. Bowel cancer screening is perhaps the most effective method to mitigate the consequences of the disease for patients and society. Largescale randomised trials show that screening with sigmoidoscopy and faecal occult blood tests reduce col...

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Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals.

BACKGROUND Colorectal cancer is the third most frequent cancer in the world. As the sojourn time for this cancer is several years and a good prognosis is associated with early stage diagnosis, screening has been implemented in a number of countries. Both screening with faecal occult blood test and flexible sigmoidoscopy have been shown to reduce mortality from colorectal cancer in randomised co...

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Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy.

BACKGROUND Screening for colorectal cancer (CRC) is widely accepted, but there is no consensus on the preferred strategy. We conducted a randomised trial comparing participation and detection rates (DR) per screenee of guaiac-based faecal occult blood test (gFOBT), immunochemical FOBT (FIT), and flexible sigmoidoscopy (FS) for CRC screening. METHODS A representative sample of the Dutch popula...

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Testing for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT).

BACKGROUND Screening for colorectal cancer (CRC) using guaiac based faecal occult blood tests (FOBT) has an estimated programme sensitivity of >60% but <30% for strictly asymptomatic CRC in a single screening round. In search for improved non-invasive tests for screening, we compared a test for faecal calprotectin (PhiCal) with a human haemoglobin immunochemical FOBT (FlexSure OBT). METHODS I...

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General practice Population based randomised study of uptake and yield of screening by flexible sigmoidoscopy compared with screening by faecal occult blood testing

Objectives: To compare the feasibility of mass screening by flexible sigmoidoscopy with screening by faecal occult blood testing (Haemoccult) and both tests combined. Design: Patients were randomised to screening by flexible sigmoidoscopy, faecal blood testing, or both tests. The flexible sigmoidoscopy examinations were performed by a general practitioner. Setting: General practice. Subjects: 3...

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ژورنال

عنوان ژورنال: Journal of Medical Screening

سال: 2019

ISSN: 0969-1413,1475-5793

DOI: 10.1177/0969141319879955